Don't believe people who say that 95 percent of infertility is due to psychological factors.

 Dear readers, I continue to introduce you to excerpts from my book "Angels drink milk".    

  Unfortunately, the practice of reproductive assistive technology does not help all couples. Even taking into account the experience and technical capabilities of Korean doctors, the constant re-equipment of clinics with state-of-the-art equipment, and much more, the percentage of treatment success reaches a maximum of 60-70%. Moreover, such a high rate is observed only in young couples under 35 years of age.

    Jin-Ho had a certain number of patients who, unfortunately, she could not help or who "went out of the race" after a series of failures. Each particular case the doctor remembered perfectly, it was her pain and tears. It remained only to pray for the higher powers to grant these couples a "miracle" pregnancy.



    At one point, a married couple from America, very beautiful, relatively young, were being treated at the Korean Medi clinic. When they arrived for the first time for an examination, it seemed that they would not have any problems with conception, outwardly almost everything was normal.

    The protocol started as usually, following the selected pattern. At the puncture, a sufficient number of mature eggs cells were taken from the wife, fertilized, and the husband's spermogram was normal. However, none of the embryos survived to the third day, and on the second day they were still too underdeveloped. And this result was several times in a row, even after changing the treatment tactics…

    There could be many reasons for this: the complete failure of the genome of the husband, whose material was added to the development of the embryo on the third day, inherited genetic breakdowns in the combined genes of the husband and the wife, unsuitable conditions for development outside the uterus. But how to explain all this to young spouses who have put so much hope, time, and money in the struggle for having children? What is most terrible, when changing the type and tactics of conducting the protocol, drugs, pills for the development of embryos and whatever, the final results were untenable.

    The couple from America repeated the protocols several times at the clinic "Korean Medi" and very much believed in success. Only in the last IVF Protocol there was a chance: one embryo survived until the third day, but it was weak in the quality of intracellular mass. However, in the heart of Dr. Kim Jin-Ho and the couple, hope was born, and the strongest supporting therapy for the development of pregnancy was prescribed.

    12 days after the transfer, the woman treacherously began to "bleed", the lower abdomen ached as on the monthly period, and that was all… a failure. Unfortunately, a test for HCG the next day confirmed the worst suspicions, pregnancy did not occur. In such cases, they say that nature cannot be changed: if a couple is not destined to have children, then all the best possibilities of modern medicine will not help.

    There are also more mysterious factors of pregnancy absence that can be treated due to the development of reproductive technologies, are autoimmune processes in the body of a woman. Few people have heard about them, but today, every seventh infertile woman has such problems. There are such cases when a woman's body contains so-called killer cells of her own immunity, which reject the embryo when it's attached, or male cells-sperm, or do not allow the fetus to develop, leading to the freezing of its development. Of course, modern 21st-century technologies in the field of fertility have several ways to suppress the immune response of aggressive killer cells. For example, such as immunoglobulin IVS, prescribed to the patient immediately after embryo transfer and later in support of pregnancy. However, sometimes even such tricks can't help you to trick on the body, at least after the first attempt of IVF.

    "You should not give up if your first attempt fails," said the doctor of one of the patients with an autoimmune factor. "You need to try and try until the result is achieved! Some are "lucky" and after one attempt of IVF get pregnant, and someget the result only after the fifth. With a positive test, you will have to be regularly checked up by an immunologist and a hematologist for the entire pregnancy, in order to restrain your cells and prevent them from affecting the development of the fetus!

    "We have not been able to get pregnant for so many years,we had a diagnosis infertility of unknown origin! We tried every treated, up to homeopathy and leeches! Was it all caused just by some immune cells?" asked the patient and her husband.

    "I have had couples with an autoimmune factor and almost all of them, even if not from the first attempt, but from the second, the third, got pregnant and eventually gave birth to a child. This is an insidious diagnosis, but it is quite treatable with the help of modern drugs. You must believe in yourself and in medicine, otherwise why did you come here?"

    "Yes, you are right, we need to try, because as they say,nothing ventured, nothing gained,"the woman agreed.

    "You should understand that there is no diagnosis of infertility of uncertain origin, there is always a reason for not getting pregnant, and only an experienced doctor can get what that reason is. Don't believe people who say that 95 percent of infertility is due to psychological factors, just the opposite, 95 percent is due to physiological reasons!"

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 Привет, мои дорогие рускоязычные подписчики и читатели! Наконец-то получилось выложить все 4 части романа "Ангелы пьют молоко"  на ресурс Литрес. Интриги и жизненные приключения главной героини -  корейского врача Ким Джин Хо набирают неожиданные обороты. Третья глава географически позиционирована в США, в четвёртой Вы будете удивлены путевыми заметками по Венгрии. Жду с нетерпением Ваших самых ценных для меня отзывов!! Англоязычный вариант третьей главы осталось только оформить, ждите обновлений на Amazon.  Книга доступна на Литрес  целиком по ссылке ниже за символическую плату https://www.litres.ru/diana-candy/angely-put-moloko/?yclid=1876234325131825294

С любовью, Ваша Ди.

Endoscopic operations on the fallopian tubes: myth or reality?

 Dear readers, I continue to introduce you to excerpts from my book "Angels drink milk". 

 Work in the laboratory and promising research took all the girl's attention, the world of science is boundless and fascinating for anyone who wants to plunge into it. Unfortunately, some seemingly obvious areas of the human body for comprehensive medical practice remain at the rudimentary stage of treatment possibilities. If we are talking about women, then an example of extreme limitations of treatment is the uterine tubes.

             The 21st century is on the calendar, but so far no clinic in the world can fully restore the function of the uterine tube after an ectopic pregnancy, hydrosalpinx[1]or other injuries. In principle, plastic surgery on tubes is not fully feasible. There are many reasons for this: it is the complexity of the organ as such[2], the simplicity of damaging the tubes[3], the microscopic size of the lumen of the tube (not more than 3 mm). The Research and invention of mechanisms for restoring uterine tubes functions were fascinating for many scientists, including long-time interested in Jin Ho. Now she had a great opportunity to work on this issue. She spent a long time studying this problem in the University laboratory;she conducted computer simulations of their operation, and wondering what could be done to help thousands of women restore the functions of this crucial organ after damaging or illness. If she comes up with a new way to treat or restore this organ "it will be not only a breakthrough in medicine but also her personal success which is important!

             One evening when she was working in the lab, it suddenly dawned on her: why hasn't humanity yet invented nano surgical endoscopic equipment[4] for examining the uterine tubes from the inside? These are such optomechanical devices that are equipped with a system for transmitting light and images, they could be used in the lumen of the uterine tubes, but the size of robot devices should really be nanoscopic[5]. The results of using endoscopes are clear and well known:

·                Ability to assess the situation in the organ, displayed on the screen of a personal computer;

·                Ability to make fast decisions;

·                Theoretically, it is possible to perform nanosurgical operations by feeding the desired instrument through the endoscope tube!

             Jin Ho's eyes lit up: she should implement these ideas in her work! Especially given the fact that nowadays real medical nanorobots have begun to appear.Within a few weeks, the draft version of the project was being worked on.

           Engineers of the research center's laboratory helped the girl simulate the operation of an endoscopic nanorobot in the lumen of a woman's uterine tubes on a computer, and Jin Ho herself made a description of the model. While working on the device, she incorporated anatomical and hemodynamic data of the human uterine tubes into a computer model of the ape's uterine tubes. The results were promising.

            Her ideas were close to sci-fi in the field of modern science. Jin Ho described in detail a nano-sized video camera positioned directly on the molecules of a special medium of a tiny nanotube inserted into the lumen of the tube. Even the substance from which the tube should be made was especial, organic.

            Further, she wrote about the possibility of using a laser beam, for example, for the purpose of gentle removing an embryo developing and attached to the tube during an ectopic pregnancy. Her research and ideas often overlapped with the field of molecular biology and was somewhat ahead of the medical technology and robots achieved so far. It offered innovative methods for treating diseases of the uterine tubes, and they were brilliant, even in fantastic.

            Jin Ho as a real scientist could anticipate some of the technical and medical developments of the coming years! Perhaps, she could call her an Oracle in the field of medicine, a divine seer, but she was very modest and did not consider her work to be anything better than the work of other students. The scientific supervisor of the leading research center at Johns Hopkins University, Professor Jack Chinzon, was surprised by the depth of the ideas of the young Korean woman:

            "Your project is brilliant, I would not have thought of such a thing! It would be necessary to describe everything correctly, and we will apply for the cover of the best medical journals! We need to ask the engineering guys to help with the simulation design of this and this models," he said, pointing at the layouts drawn in the computer program. Chinzon spent a long time praising Jin Ho's ideas, but secretly doubted that they would be implemented in practice.

 



[1] A hydrosalpinx is a condition that occurs when the fallopian tube is blocked and fills with serous or clear fluid near the ovary (distal to the uterus).

[2]The uterine tubes are unpredictable, they can contract, resembling muscles, and they have microscopic cilia inside them, which help the cell.

[3] For example, infection, adhesions, impaired motility of the inner cilia.

[4] Endoscopy is the insertion of a long, thin tube directly into the body to observe an internal organ or tissue in detail. It can also be used to carry out other tasks including imaging and minor surgery.

[5] One nanometer is equivalent to a billionth of a meter. This is about the length of five to ten atoms in a row. A nanometer is to a meter what a football is to the entire earth. The term nanotechnology is used to describe the specific and controlled measurement, development, manufacture and use of nanomaterials.

Visiting the Snow Queen (The method of embryo cryopreservation)

 Dear readers, I continue to introduce you to excerpts from my book  "Angels drink milk".               " F...